DDHD2

Across TCGA patient cohorts, DDHD2 mutation is significantly associated with the RNA expression of many other genes, with 2,627 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DDHD2-associated genes across cancer lineages are OFD1P5Y, RNA5SP436, and KCND3-AS1. Each is linked with DDHD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both DDHD2-to-partner and partner-to-DDHD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OFD1P5Y grouped by DDHD2-low versus DDHD2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDHD2→partner) and Y-score (partner→DDHD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OFD1P5Y →	+0.004	+4.229	.001	.006	3	3
BLCA	RNA5SP436 →	+0.193	+5.048	<.001	.002	3	3
READ	KCND3-AS1 →	+0.293	+5.653	<.001	.003	3	2
BRCA	ARL2BPP6 →	+0.186	+5.971	<.001	.002	3	2
CESC	RNA5SP432 →	+0.396	+5.539	<.001	.004	3	2
CESC	RNU5E-8P →	+0.481	+6.144	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,627 associations by consensus.

OFD1P5Y by DDHD2 expression — BLCA

Explore this box plot interactively →