DDHD1

Across TCGA pan-cancer cohorts, DDHD1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DDHD1 data layer compared with 29 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher DDHD1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated DDHD1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and GBM show a favorable association.

LUAD, PDAC, and CCRCC are the cancer types where DDHD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	All	0.923	1.000	.008	5	view →
PDAC	OS	Tertile	II,III,IV	0.360	0.581	.021	4	view →
CCRCC	OS	Median	III,IV	1.000	0.353	.022	3	view →
GBM	DFS	Quartile	All	0.846	0.672	.015	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DDHD1–LUAD (OS)

Open the LUAD breakdown →