DDHD1

Across TCGA patient cohorts, DDHD1 mutation is significantly associated with the RNA expression of many other genes, with 2,733 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DDHD1-associated genes across cancer lineages are ANKRD33B-AS1, MIR4774, and RNU6-1318P. Each is linked with DDHD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DDHD1-to-partner and partner-to-DDHD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANKRD33B-AS1 grouped by DDHD1-low versus DDHD1-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDHD1→partner) and Y-score (partner→DDHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	ANKRD33B-AS1 →	+0.187	+6.681	<.001	<.001	3	3
READ	MIR4774 →	+0.841	+6.257	<.001	.001	3	3
COAD	RNU6-1318P →	+1.058	+3.067	<.001	.008	3	3
COAD	TRAJ11 →	+1.267	+3.373	<.001	.004	3	3
COAD	MTCO2P23 →	+0.246	+4.399	<.001	.006	3	3
COAD	RN7SL97P →	+0.476	+3.271	<.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,733 associations by consensus.

ANKRD33B-AS1 by DDHD1 expression — READ

Explore this box plot interactively →