DDC

Across TCGA patient cohorts, DDC protein abundance is significantly associated with the RNA expression of many other genes, with 5,810 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible DDC-associated genes across cancer lineages are RNU6-26P, CD44, and BTBD7P1. Each is linked with DDC in more than 2 cancer types. Because this analysis shows association rather than direction, both DDC-to-partner and partner-to-DDC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDC versus RNU6-26P in COAD, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DDC→partner) and Y-score (partner→DDC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-26P →	-1.092	-0.516	<.001	<.001	3	3
CCRCC	CD44 →	-0.717	-0.481	.001	<.001	3	3
OV	BTBD7P1 →	+0.746	+0.940	.003	.009	3	2
OV	CFAP57 →	-0.539	-0.750	.002	.003	3	2
CCRCC	AOC1 →	+2.062	+0.429	<.001	<.001	3	2
OV	RAP1GAP →	+1.766	+1.266	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,810 associations by consensus.

DDC vs RNU6-26P — COAD

Explore this scatter interactively →