DDA1

Across TCGA patient cohorts, DDA1 protein abundance is significantly associated with the protein abundance of many other proteins, with 19,825 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DDA1-associated proteins across cancer lineages are SRSF3, TRIR, and SRRT. Each is linked with DDA1 in more than 7 cancer types. Because this analysis shows association rather than direction, both DDA1-to-partner and partner-to-DDA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DDA1 versus SRSF3 in GBM, with a Pearson correlation of 0.68.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DDA1→partner) and Y-score (partner→DDA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SRSF3 →	+0.334	+0.329	<.001	<.001	3	8
GBM	TRIR →	+0.456	+0.264	<.001	<.001	3	8
GBM	SRRT →	+0.289	+0.299	<.001	<.001	3	7
GBM	KHSRP →	+0.281	+0.267	<.001	<.001	3	7
OV	DDB1 →	+0.269	+0.505	<.001	<.001	2	8
BRCA	RANBP3 →	+0.236	+0.237	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,825 associations by consensus.

DDA1 vs SRSF3 — GBM

Explore this scatter interactively →