DCXR

Across TCGA patient cohorts, DCXR protein abundance is significantly associated with the RNA expression of many other genes, with 11,322 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DCXR-associated genes across cancer lineages are TMSB10, LAMC2, and ACTB. Each is linked with DCXR in more than 5 cancer types. Because this analysis shows association rather than direction, both DCXR-to-partner and partner-to-DCXR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCXR versus TMSB10 in BRCA, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCXR→partner) and Y-score (partner→DCXR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TMSB10 →	-0.832	-0.563	<.001	<.001	3	6
BRCA	LAMC2 →	-1.686	-0.427	<.001	.008	3	5
OV	ACTB →	-0.629	-0.432	.009	.001	3	5
BRCA	MMP1 →	-2.014	-0.423	<.001	<.001	3	5
OV	CD276 →	-0.683	-0.407	.003	.005	3	4
BRCA	IL4I1 →	-1.483	-0.818	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,322 associations by consensus.

DCXR vs TMSB10 — BRCA

Explore this scatter interactively →