DCXR-DT

Across TCGA pan-cancer cohorts, DCXR-DT RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated DCXR-DT data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher DCXR-DT RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated DCXR-DT expression acts as an unfavorable survival marker, although some lineages such as BRCA and KIRP show a favorable association.

BRCA, ACC, and KIRC are the cancer types where DCXR-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Median	II,III,IV	0.546	0.474	<.001	92	view →
ACC	DFS	Median	All	0.202	0.705	<.001	74	view →
KIRC	DFS	Median	III,IV	0.676	0.797	<.001	65	view →
KIRP	OS	Tertile	III,IV	0.712	0.297	.004	44	view →
ESCA	DFS	Quartile	III,IV	0.243	0.529	<.001	30	view →
UCS	DFS	Tertile	IV	0.239	0.942	.024	24	view →
LGG	OS	Tertile	All	0.935	0.830	<.001	23	view →
STAD	DFS	Tertile	All	0.579	0.685	.028	18	view →
LUAD	DFS	Tertile	All	0.475	0.170	.006	16	view →
PAAD	DFS	Quartile	All	0.450	0.206	.016	15	view →
CHOL	OS	Quartile	II,III,IV	0.245	0.795	.019	13	view →
READ	DFS	Quartile	All	0.694	0.955	.007	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

DCXR-DT–BRCA (DFS)

Open the BRCA breakdown →