DCX

Across TCGA cell cohorts, DCX mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DCX-associated genes across cancer lineages are WFDC11, GALP, and GYS2. Each is linked with DCX in more than 1 cancer types. Because this analysis shows association rather than direction, both DCX-to-partner and partner-to-DCX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WFDC11 grouped by DCX-low versus DCX-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCX→partner) and Y-score (partner→DCX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	WFDC11 →	+0.030	+4.539	<.001	.007	3	1
BLOOD_Leukemia	GALP →	+0.051	+5.786	<.001	<.001	3	1
LARGE_INTESTINE	GYS2 →	+0.024	+2.760	.002	.003	3	1
LARGE_INTESTINE	KRTAP10-10 →	+0.052	+2.347	<.001	.007	3	1
LARGE_INTESTINE	CD300H →	+0.022	+3.192	<.001	.002	3	1
LARGE_INTESTINE	TNRC6C →	+0.821	+3.212	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

WFDC11 by DCX expression — BLOOD_Leukemia

Explore this box plot interactively →