DCUN1D5

Across TCGA pan-cancer cohorts, DCUN1D5 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DCUN1D5 data layer compared with 26 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher DCUN1D5 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated DCUN1D5 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

PDAC, LSCC, and CCRCC are the cancer types where DCUN1D5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	III,IV	0.220	0.573	.005	30	view →
LSCC	DFS	Quartile	All	0.854	0.558	.013	7	view →
CCRCC	DFS	Quartile	III,IV	0.771	1.000	.023	3	view →
LUAD	DFS	Median	III,IV	0.972	0.508	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DCUN1D5–PDAC (OS)

Open the PDAC breakdown →