DCUN1D2

Across TCGA patient cohorts, DCUN1D2 mutation is significantly associated with the RNA expression of many other genes, with 2,073 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCUN1D2-associated genes across cancer lineages are M6PRP1, RNA5SP422, and OR10G3. Each is linked with DCUN1D2 in more than 2 cancer types. Because this analysis shows association rather than direction, both DCUN1D2-to-partner and partner-to-DCUN1D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, M6PRP1 grouped by DCUN1D2-low versus DCUN1D2-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCUN1D2→partner) and Y-score (partner→DCUN1D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	M6PRP1 →	+0.043	+4.337	<.001	.001	3	3
UCEC	RNA5SP422 →	+1.035	+2.308	<.001	.002	3	3
BLCA	OR10G3 →	+0.049	+5.788	<.001	.003	3	2
BLCA	MTND5P21 →	+0.083	+5.038	.001	.009	3	2
BLCA	LINC02252 →	+0.143	+5.251	<.001	.006	3	2
BLCA	MIR6752 →	+0.469	+5.685	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,073 associations by consensus.

M6PRP1 by DCUN1D2 expression — LUSC

Explore this box plot interactively →