DCUN1D2

Across TCGA pan-cancer cohorts, DCUN1D2 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of DCUN1D2’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where DCUN1D2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DCUN1D2 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

COAD, THCA, and KIRC are the cancer types where DCUN1D2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DCUN1D2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	+0.949	<.001	11	view →
THCA	Male	All	−0.354	<.001	10	view →
KIRC	Male	II,III,IV	−0.483	<.001	8	view →
LIHC	Female	II,III,IV	+0.808	<.001	7	view →
CHOL	Male	All	+1.548	<.001	5	view →
KICH	All	All	−0.575	<.001	5	view →
LUAD	Female	II,III,IV	−0.510	<.001	5	view →
KIRP	Male	All	−0.382	.008	4	view →
READ	All	II,III,IV	+0.887	.022	3	view →
UCEC	All	IV	−0.730	.047	2	view →
ESCA	All	All	+0.605	.013	2	view →
BLCA	Female	All	+0.536	.040	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

DCUN1D2–COAD

Open the COAD breakdown →