DCUN1D1

Across TCGA patient cohorts, DCUN1D1 mutation is significantly associated with the RNA expression of many other genes, with 3,533 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCUN1D1-associated genes across cancer lineages are MIR5580, IGHD3-16, and RNA5SP176. Each is linked with DCUN1D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCUN1D1-to-partner and partner-to-DCUN1D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR5580 grouped by DCUN1D1-low versus DCUN1D1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCUN1D1→partner) and Y-score (partner→DCUN1D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR5580 →	+0.981	+3.958	<.001	.006	3	2
UCEC	IGHD3-16 →	+0.951	+1.873	<.001	.001	3	2
UCEC	RNA5SP176 →	+0.295	+3.306	<.001	.003	3	2
BRCA	MIR8062 →	+0.592	+8.471	<.001	.005	3	1
BRCA	RNA5SP346 →	+0.267	+7.731	<.001	.009	3	1
BRCA	RNU6-648P →	+0.458	+8.055	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,533 associations by consensus.

MIR5580 by DCUN1D1 expression — COAD

Explore this box plot interactively →