DCTN6

Across TCGA patient cohorts, DCTN6 protein abundance is significantly associated with the RNA expression of many other genes, with 15,951 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DCTN6-associated genes across cancer lineages are PDE1A, HROB, and DBF4B. Each is linked with DCTN6 in more than 5 cancer types. Because this analysis shows association rather than direction, both DCTN6-to-partner and partner-to-DCTN6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCTN6 versus PDE1A in GBM, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCTN6→partner) and Y-score (partner→DCTN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PDE1A →	+1.250	+0.379	<.001	<.001	3	6
HNSC	HROB →	-0.660	-0.199	.001	<.001	3	6
HNSC	DBF4B →	-0.637	-0.202	<.001	<.001	3	6
UCEC	LMOD1 →	+1.000	+0.156	.002	.009	3	6
UCEC	WBP1L →	+0.445	+0.200	.002	<.001	3	6
BRCA	MYBL2 →	-1.083	-0.231	.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,951 associations by consensus.

DCTN6 vs PDE1A — GBM

Explore this scatter interactively →