DCTN6

Across TCGA patient cohorts, DCTN6 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCTN6-associated genes across cancer lineages are MEK1 and ATM. Each is linked with DCTN6 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCTN6-to-partner and partner-to-DCTN6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEK1 grouped by DCTN6-low versus DCTN6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCTN6→partner) and Y-score (partner→DCTN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.433	+3.000	.040	.037	1	1
UCEC	ATM →	-0.662	-3.000	.011	.037	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MEK1 by DCTN6 expression — UCEC

Explore this box plot interactively →