DCTN2

Across TCGA patient cohorts, DCTN2 protein abundance is significantly associated with the protein abundance of many other proteins, with 31,215 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DCTN2-associated proteins across cancer lineages are DCTN1, LHPP, and BAZ1A. Each is linked with DCTN2 in more than 9 cancer types. Because this analysis shows association rather than direction, both DCTN2-to-partner and partner-to-DCTN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCTN2 versus DCTN1 in OV, with a Pearson correlation of 0.53.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DCTN2→partner) and Y-score (partner→DCTN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DCTN1 →	+0.624	+0.828	.001	<.001	3	10
PDAC	LHPP →	+0.654	+0.323	<.001	<.001	3	10
LUAD	BAZ1A →	-0.350	-0.130	<.001	<.001	3	9
BRCA	RFC1_T506 →	-1.207	-0.201	<.001	<.001	3	9
PDAC	SEPTIN7 →	+0.362	+0.310	<.001	<.001	3	9
COAD	SMC4 →	-0.581	-0.233	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 31,215 associations by consensus.

DCTN2 vs DCTN1 — OV

Explore this scatter interactively →