Across TCGA cell cohorts, DCTN1 mutation is significantly associated with the RNA expression of many other genes, with 74 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DCTN1-associated genes across cancer lineages are ZC3H10, OR11H2, and PPDPFL. Each is linked with DCTN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCTN1-to-partner and partner-to-DCTN1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCTN1→partner) and Y-score (partner→DCTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ZC3H10 →	+0.441	+3.064	.004	.009	3	2
BLOOD_Leukemia	OR11H2 →	+0.037	+3.201	<.001	.005	3	2
BREAST	PPDPFL →	+0.073	+3.415	<.001	.004	3	1
BREAST	OR51L1 →	+0.021	+3.781	<.001	.009	3	1
BREAST	OR51T1 →	+0.028	+3.781	<.001	.009	3	1
BREAST	KRTAP4-2 →	+0.016	+3.781	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 74 associations by consensus.

Exploration

DCTN1 survival (RNA) · tumor vs normal (RNA) · all DCTN1 data types