DCTD

Across TCGA cell cohorts, DCTD RNA expression is significantly associated with the go_rna of many other GO terms, with 4,536 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DCTD-associated GO terms across cancer lineages are R-loop processing, Positive regulation of protein binding, and Positive regulation of lamellipodium assembly. Each is linked with DCTD in more than 12 cancer types. Because this analysis shows association rather than direction, both DCTD-to-partner and partner-to-DCTD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, R-loop processing grouped by DCTD-low versus DCTD-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DCTD→partner) and Y-score (partner→DCTD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	R-loop processing →	+0.093	+0.844	<.001	<.001	3	13
BONE	Positive regulation of protein binding →	+0.138	+1.583	<.001	<.001	3	11
BREAST	Positive regulation of lamellipodium assembly →	+0.105	+1.317	<.001	<.001	3	9
BONE	Positive regulation of cellular response to transforming growth factor beta stimulus →	+0.135	+1.947	.001	.003	3	9
CNS	Regulation of SREBP signaling pathway →	+0.074	+0.627	<.001	<.001	3	9
BONE	Positive regulation of transforming growth factor beta receptor signaling pathway →	+0.135	+1.947	.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,536 associations by consensus.

R-loop processing by DCTD expression — STOMACH

Explore this box plot interactively →