DCST1-AS1

Across TCGA pan-cancer cohorts, DCST1-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of DCST1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where DCST1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DCST1-AS1 is over-expressed in tumor.

BLCA, LUAD, and THCA are the cancer types where DCST1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DCST1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	+1.951	<.001	12	view →
LUAD	Female	III,IV	+1.516	<.001	11	view →
THCA	Female	II,III,IV	+0.952	<.001	11	view →
KIRP	All	III,IV	+0.766	<.001	11	view →
KIRC	All	II,III,IV	+0.308	<.001	10	view →
LIHC	Male	II,III,IV	+1.772	<.001	9	view →
UCEC	All	III,IV	+1.474	<.001	6	view →
LUSC	Female	All	+1.262	<.001	6	view →
BRCA	All	III,IV	+0.897	<.001	6	view →
COAD	All	II,III,IV	+0.451	.004	6	view →
CHOL	All	All	+1.023	.005	5	view →
STAD	Male	All	+0.804	<.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

DCST1-AS1–BLCA

Open the BLCA breakdown →