DCP1A

Across TCGA patient cohorts, DCP1A mutation is significantly associated with the RNA expression of many other genes, with 858 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCP1A-associated genes across cancer lineages are OFD1P7Y, SPTLC1P2, and GAGE12H. Each is linked with DCP1A in more than 1 cancer types. Because this analysis shows association rather than direction, both DCP1A-to-partner and partner-to-DCP1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OFD1P7Y grouped by DCP1A-low versus DCP1A-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCP1A→partner) and Y-score (partner→DCP1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	OFD1P7Y →	+0.030	+7.174	<.001	<.001	3	2
BLCA	SPTLC1P2 →	+0.295	+3.670	<.001	.001	3	2
BLCA	GAGE12H →	+0.161	+4.718	<.001	.003	3	2
SKCM	SLC11A1 →	+0.672	+2.706	.004	.003	3	2
SKCM	OR8A2P →	+0.123	+2.182	<.001	.006	3	2
SKCM	RN7SL524P →	+0.066	+2.216	.003	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 858 associations by consensus.

OFD1P7Y by DCP1A expression — CESC

Explore this box plot interactively →