DCLRE1CP1

Across TCGA patient cohorts, DCLRE1CP1 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCLRE1CP1-associated genes across cancer lineages are RNY4P14, RNU6-147P, and RNU6-831P. Each is linked with DCLRE1CP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCLRE1CP1-to-partner and partner-to-DCLRE1CP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNY4P14 grouped by DCLRE1CP1-low versus DCLRE1CP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCLRE1CP1→partner) and Y-score (partner→DCLRE1CP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNY4P14 →	+0.499	+5.722	<.001	.001	3	1
UCEC	RNU6-147P →	+0.442	+4.551	.002	.009	3	1
UCEC	RNU6-831P →	+0.465	+5.123	<.001	.004	3	1
UCEC	TRAJ11 →	+0.940	+4.398	.002	.006	3	1
UCEC	RNU6-466P →	+0.735	+4.661	<.001	.004	3	1
UCEC	DHFRP5 →	+0.114	+5.582	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

RNY4P14 by DCLRE1CP1 expression — UCEC

Explore this box plot interactively →