DCLK2

Across TCGA patient cohorts, DCLK2 mutation is significantly associated with the RNA expression of many other genes, with 4,442 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCLK2-associated genes across cancer lineages are BNIP3, ELOCP30, and H3P3. Each is linked with DCLK2 in more than 2 cancer types. Because this analysis shows association rather than direction, both DCLK2-to-partner and partner-to-DCLK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BNIP3 grouped by DCLK2-low versus DCLK2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCLK2→partner) and Y-score (partner→DCLK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	BNIP3 →	+0.813	+2.510	<.001	.009	3	3
CESC	ELOCP30 →	+0.066	+4.144	<.001	.009	3	2
CESC	H3P3 →	+0.169	+3.839	<.001	.004	3	2
CESC	MIR4510 →	+0.195	+4.342	<.001	.007	3	2
CESC	RN7SL248P →	+0.080	+5.584	<.001	.001	3	2
HNSC	SNORD113-6 →	+0.348	+6.781	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,442 associations by consensus.

BNIP3 by DCLK2 expression — SKCM

Explore this box plot interactively →