DCHS1

Across TCGA patient cohorts, DCHS1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,881 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DCHS1-associated genes across cancer lineages are PCOLCE, TGFB1I1, and ADAMTS12. Each is linked with DCHS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both DCHS1-to-partner and partner-to-DCHS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCHS1 versus PCOLCE in OV, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCHS1→partner) and Y-score (partner→DCHS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PCOLCE →	+1.091	+0.438	<.001	<.001	3	8
OV	TGFB1I1 →	+1.512	+0.543	<.001	<.001	3	8
BRCA	ADAMTS12 →	+1.310	+0.593	<.001	<.001	3	8
OV	PRKD1 →	+0.835	+0.409	<.001	<.001	3	8
BRCA	FERMT2 →	+1.054	+0.561	<.001	<.001	3	8
OV	MEDAG →	+1.686	+0.446	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,881 associations by consensus.

DCHS1 vs PCOLCE — OV

Explore this scatter interactively →