DCHS1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DCHS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,477 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible DCHS1-associated GO terms across cancer lineages are Protein-DNA complex organization, Epigenetic regulation of gene expression, and Regulation of myoblast fusion. Each is linked with DCHS1 in more than 13 cancer types. Because this analysis shows association rather than direction, both DCHS1-to-partner and partner-to-DCHS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-DNA complex organization grouped by DCHS1-low versus DCHS1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DCHS1→partner) and Y-score (partner→DCHS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEProtein-DNA complex organization →+0.076+2.025.002<.001314
OVARYEpigenetic regulation of gene expression →+0.057+0.649<.001<.001313
UPPER_AERODIGESTIVE_TRACTRegulation of myoblast fusion →+0.144+0.259<.001.002312
UPPER_AERODIGESTIVE_TRACTNegative regulation of syncytium formation by plasma membrane fusion →+0.125+0.212<.001.001312
LUNG_SCLCHeterochromatin organization →+0.093+2.416<.001<.001312
LUNG_SCLCRegulation of double-strand break repair →+0.086+2.889<.001<.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,477 associations by consensus.

Protein-DNA complex organization by DCHS1 expression — BONE

Box plot of Protein-DNA complex organization in DCHS1-low vs DCHS1-high samples in BONE.

Explore this box plot interactively →

Exploration