Across TCGA cell cohorts, DCDC2B mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible DCDC2B-associated genes across cancer lineages are OR4E1, ZSCAN1, and TBL1Y. Each is linked with DCDC2B in more than 1 cancer types. Because this analysis shows association rather than direction, both DCDC2B-to-partner and partner-to-DCDC2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCDC2B→partner) and Y-score (partner→DCDC2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	OR4E1 →	+0.099	+5.321	<.001	.005	3	2
PANCREAS	ZSCAN1 →	+0.039	+5.000	<.001	.006	3	1
PANCREAS	TBL1Y →	+0.006	+5.614	<.001	.002	3	1
BLOOD_Leukemia	OR10R2 →	+1.283	+4.551	.006	.004	3	1
LUNG_SCLC	CEACAM8 →	+0.113	+4.523	<.001	.003	3	1
LUNG_SCLC	SMCP →	+0.047	+4.643	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

DCDC2B survival (RNA) · tumor vs normal (RNA) · all DCDC2B data types