DCAKD

Across TCGA patient cohorts, DCAKD mutation is significantly associated with the RNA expression of many other genes, with 193 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCAKD-associated genes across cancer lineages are SNRPCP14, RNU6-1318P, and STAG3L4. Each is linked with DCAKD in more than 1 cancer types. Because this analysis shows association rather than direction, both DCAKD-to-partner and partner-to-DCAKD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPCP14 grouped by DCAKD-low versus DCAKD-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAKD→partner) and Y-score (partner→DCAKD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SNRPCP14 →	+0.414	+3.463	<.001	.006	3	2
UCEC	RNU6-1318P →	+0.395	+3.189	<.001	.001	3	2
UCEC	STAG3L4 →	+0.691	+3.467	<.001	.002	3	1
UCEC	NCS1 →	+0.774	+3.191	.005	.009	3	1
UCEC	CAMTA2 →	+0.605	+3.202	<.001	.009	3	1
UCEC	PSMD11 →	+0.547	+3.346	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 193 associations by consensus.

SNRPCP14 by DCAKD expression — COAD

Explore this box plot interactively →