DCAKD

Across TCGA pan-cancer cohorts, DCAKD RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated DCAKD data layer compared with 1 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher DCAKD RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated DCAKD expression acts as an unfavorable survival marker, although some lineages such as UCEC and BRCA show a favorable association.

UCEC, BRCA, and KIRC are the cancer types where DCAKD RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.729	0.564	.001	104	view →
BRCA	DFS	Tertile	III,IV	0.933	0.823	.005	61	view →
KIRC	DFS	Tertile	IV	0.363	0.804	<.001	55	view →
HNSC	OS	Median	All	0.748	0.615	.002	47	view →
LUSC	OS	Median	II,III,IV	0.821	0.638	<.001	46	view →
SKCM	DFS	Tertile	All	0.690	0.858	.003	28	view →
KICH	OS	Median	All	0.671	1.000	.002	20	view →
PAAD	DFS	Tertile	All	0.565	0.338	.007	17	view →
LIHC	DFS	Tertile	All	0.339	0.496	.003	16	view →
ACC	DFS	Quartile	All	0.129	0.635	.008	16	view →
BLCA	OS	Tertile	All	0.270	0.560	.006	12	view →
READ	OS	Quartile	III,IV	0.962	0.577	.014	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

DCAKD–UCEC (DFS)

Open the UCEC breakdown →