DCAF8L1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DCAF8L1 mutation is significantly associated with the RNA expression of many other genes, with 5,956 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCAF8L1-associated genes across cancer lineages are CEP76, ATP6V1A, and TENT4A. Each is linked with DCAF8L1 in more than 3 cancer types. Because this analysis shows association rather than direction, both DCAF8L1-to-partner and partner-to-DCAF8L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF8L1→partner) and Y-score (partner→DCAF8L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCEP76 →+0.342+1.461<.001<.00134
UCECATP6V1A →+0.353+1.669.003<.00134
LUADTENT4A →+0.353+2.266.008.00534
UCECUSP1 →+0.479+1.747.001<.00134
UCECKIF15 →+0.557+2.294<.001<.00134
UCECSNRNP48 →+0.370+1.390<.001.00234
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,956 associations by consensus.

Exploration