Across TCGA cell cohorts, DCAF8L1 mutation is significantly associated with the RNA expression of many other genes, with 48 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DCAF8L1-associated genes across cancer lineages are MC2R, EPPIN, and GSC. Each is linked with DCAF8L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCAF8L1-to-partner and partner-to-DCAF8L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF8L1→partner) and Y-score (partner→DCAF8L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MC2R →	+0.003	+3.969	<.001	.009	3	2
BLOOD_Leukemia	EPPIN →	+0.004	+3.922	.004	.002	3	1
BLOOD_Leukemia	GSC →	+1.267	+3.948	<.001	.003	3	1
BLOOD_Leukemia	DPT →	+1.252	+4.091	<.001	.002	3	1
BLOOD_Leukemia	RGR →	+0.017	+3.684	.008	.004	3	1
BLOOD_Leukemia	PCDH19 →	+0.197	+4.415	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Exploration

DCAF8L1 survival (RNA) · tumor vs normal (RNA) · all DCAF8L1 data types