DCAF7

Across TCGA pan-cancer cohorts, DCAF7 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated DCAF7 data layer compared with 27 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher DCAF7 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated DCAF7 expression acts as an unfavorable survival marker, although some lineages such as GBM and LUAD show a favorable association.

PDAC, UCEC, and HNSC are the cancer types where DCAF7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	III,IV	0.401	0.885	.002	26	view →
UCEC	OS	Median	II,III,IV	0.567	1.000	.004	24	view →
HNSC	OS	Tertile	All	0.605	0.831	.017	8	view →
GBM	DFS	Tertile	All	0.480	0.256	.019	6	view →
LUAD	DFS	Tertile	III,IV	0.995	0.412	.031	6	view →
CCRCC	DFS	Tertile	III,IV	0.981	0.186	.036	2	view →
LSCC	DFS	Tertile	III,IV	0.713	1.000	.040	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

DCAF7–PDAC (DFS)

Open the PDAC breakdown →