DCAF7

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DCAF7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,367 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DCAF7-associated GO terms across cancer lineages are Positive regulation of mitotic cytokinesis, Positive regulation of cytokinesis, and Positive regulation of mRNA catabolic process. Each is linked with DCAF7 in more than 15 cancer types. Because this analysis shows association rather than direction, both DCAF7-to-partner and partner-to-DCAF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitotic cytokinesis grouped by DCAF7-low versus DCAF7-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF7→partner) and Y-score (partner→DCAF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTPositive regulation of mitotic cytokinesis →+0.167+0.967<.001.002316
UPPER_AERODIGESTIVE_TRACTPositive regulation of cytokinesis →+0.132+1.026<.001<.001316
UPPER_AERODIGESTIVE_TRACTPositive regulation of mRNA catabolic process →+0.073+1.010.004.008316
LUNG_NSCLC_LUSCRegulation of microtubule cytoskeleton organization →+0.068+0.971<.001<.001315
BONENucleosome organization →+0.120+0.969<.001<.001315
STOMACHEpigenetic regulation of gene expression →+0.078+0.905<.001.008315
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,367 associations by consensus.

Positive regulation of mitotic cytokinesis by DCAF7 expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Positive regulation of mitotic cytokinesis in DCAF7-low vs DCAF7-high samples in UPPER_AERODIGESTIVE_TRACT.

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Exploration