DCAF5

Across TCGA pan-cancer cohorts, DCAF5 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated DCAF5 data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher DCAF5 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DCAF5 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

CCRCC, HNSC, and PDAC are the cancer types where DCAF5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.928	0.128	.014	10	view →
HNSC	OS	Tertile	IV	0.860	0.616	.024	3	view →
PDAC	OS	Quartile	III,IV	0.421	0.977	.021	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

DCAF5–CCRCC (DFS)

Open the CCRCC breakdown →