DCAF5

Across TCGA patient cohorts, DCAF5 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCAF5-associated genes across cancer lineages are STAT3_pY705, TFRC, and FoxM1. Each is linked with DCAF5 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCAF5-to-partner and partner-to-DCAF5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STAT3_pY705 grouped by DCAF5-low versus DCAF5-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF5→partner) and Y-score (partner→DCAF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	STAT3_pY705 →	-0.330	-2.309	.005	.033	3	2
UCEC	TFRC →	+0.356	+1.678	.036	.021	3	2
COAD	FoxM1 →	+0.369	+2.330	.021	.020	3	2
COAD	p90 RSK →	+0.297	+2.330	.012	.020	3	2
UCEC	eIF4E →	+0.136	+1.777	.044	.002	3	1
UCEC	ACC1 →	+0.270	+2.502	.020	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

STAT3_pY705 by DCAF5 expression — COAD

Explore this box plot interactively →