DCAF4L2

Across TCGA patient cohorts, DCAF4L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,588 significant associations in total. LGG shows the largest number of these associations.

The most reproducible DCAF4L2-associated GO terms across cancer lineages are Telomere maintenance, Regulation of DNA-directed DNA polymerase activity, and Regulation of microtubule-based process. Each is linked with DCAF4L2 in more than 12 cancer types. Because this analysis shows association rather than direction, both DCAF4L2-to-partner and partner-to-DCAF4L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere maintenance grouped by DCAF4L2-low versus DCAF4L2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF4L2→partner) and Y-score (partner→DCAF4L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Telomere maintenance →	+0.070	+0.230	<.001	.002	3	11
STAD	Regulation of DNA-directed DNA polymerase activity →	+0.074	+0.229	<.001	.002	3	11
ESCA	Regulation of microtubule-based process →	+0.051	+0.597	<.001	.006	1	13
STAD	Nucleus organization →	+0.070	+0.247	<.001	.001	3	11
STAD	Telomerase RNA localization →	+0.066	+0.227	<.001	.002	3	10
STAD	Positive regulation of organelle assembly →	+0.085	+0.290	<.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,588 associations by consensus.

Telomere maintenance by DCAF4L2 expression — STAD

Explore this box plot interactively →