DCAF4L2

Across TCGA patient cohorts, DCAF4L2 mutation is significantly associated with the RNA expression of many other genes, with 4,508 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCAF4L2-associated genes across cancer lineages are CDCA2, HMG20B, and FANCC. Each is linked with DCAF4L2 in more than 4 cancer types. Because this analysis shows association rather than direction, both DCAF4L2-to-partner and partner-to-DCAF4L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDCA2 grouped by DCAF4L2-low versus DCAF4L2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF4L2→partner) and Y-score (partner→DCAF4L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDCA2 →	+0.548	+1.536	.001	.002	3	5
UCEC	HMG20B →	+0.295	+2.108	.009	.002	3	5
UCEC	FANCC →	+0.355	+1.695	.001	.005	3	5
UCEC	CDC45 →	+0.569	+2.075	<.001	<.001	3	5
UCEC	MCM6 →	+0.407	+1.347	.009	.007	2	5
UCEC	GPATCH3 →	+0.313	+1.790	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,508 associations by consensus.

CDCA2 by DCAF4L2 expression — UCEC

Explore this box plot interactively →