DCAF4L2

Across TCGA cell cohorts, DCAF4L2 mutation is significantly associated with the RNA expression of many other genes, with 91 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible DCAF4L2-associated genes across cancer lineages are ODF1, SOX11, and PTPN5. Each is linked with DCAF4L2 in more than 2 cancer types. Because this analysis shows association rather than direction, both DCAF4L2-to-partner and partner-to-DCAF4L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ODF1 grouped by DCAF4L2-low versus DCAF4L2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF4L2→partner) and Y-score (partner→DCAF4L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ODF1 →	+0.011	+3.700	<.001	.009	3	2
SKIN	SOX11 →	+1.623	+3.520	<.001	.005	3	2
BLOOD_Leukemia	PTPN5 →	+0.370	+2.934	.002	.008	2	3
LARGE_INTESTINE	NSUN7 →	+1.267	+3.212	<.001	.006	3	2
LUNG_NSCLC_LUSC	GAPT →	+0.039	+3.807	.006	.003	3	1
LUNG_NSCLC_LUSC	TSPYL6 →	+0.078	+3.807	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 91 associations by consensus.

ODF1 by DCAF4L2 expression — SKIN

Explore this box plot interactively →