DCAF4

Across TCGA patient cohorts, DCAF4 protein abundance is significantly associated with the RNA expression of many other genes, with 2,158 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DCAF4-associated genes across cancer lineages are SNW1, DICER1, and PPP4R3A. Each is linked with DCAF4 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCAF4-to-partner and partner-to-DCAF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DCAF4 versus SNW1 in BRCA, with a Pearson correlation of -0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF4→partner) and Y-score (partner→DCAF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SNW1 →	-0.483	-0.464	<.001	.007	3	1
BRCA	DICER1 →	-1.347	-0.547	<.001	.001	3	1
BRCA	PPP4R3A →	-0.878	-0.547	<.001	.001	3	1
BRCA	UQCC1 →	-0.738	-0.497	.009	.003	3	1
BRCA	IFT52 →	-0.605	-0.593	.003	.008	3	1
BRCA	STK4 →	-0.854	-0.505	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,158 associations by consensus.

DCAF4 vs SNW1 — BRCA

Explore this scatter interactively →