DCAF4

Across TCGA cell cohorts, DCAF4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,907 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DCAF4-associated GO terms across cancer lineages are Spliceosome-depend formation of circular RNA, Monoubiquitinated protein deubiquitination, and rRNA transcription. Each is linked with DCAF4 in more than 10 cancer types. Because this analysis shows association rather than direction, both DCAF4-to-partner and partner-to-DCAF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spliceosome-depend formation of circular RNA grouped by DCAF4-low versus DCAF4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF4→partner) and Y-score (partner→DCAF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Spliceosome-depend formation of circular RNA →	+0.207	+1.218	<.001	<.001	3	11
OVARY	Monoubiquitinated protein deubiquitination →	+0.099	+0.558	<.001	.001	3	10
PANCREAS	rRNA transcription →	+0.085	+1.058	<.001	<.001	3	10
PANCREAS	Positive regulation of telomerase RNA localization to Cajal body →	+0.112	+1.406	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	tRNA transcription →	+0.090	+1.197	.003	.001	3	9
PANCREAS	Transcription initiation at RNA polymerase I promoter →	+0.108	+1.071	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,907 associations by consensus.

Spliceosome-depend formation of circular RNA by DCAF4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →