DCAF4

Across TCGA cell cohorts, DCAF4 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DCAF4-associated genes across cancer lineages are EPPIN, OR9K2, and ARSH. Each is linked with DCAF4 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCAF4-to-partner and partner-to-DCAF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EPPIN grouped by DCAF4-low versus DCAF4-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF4→partner) and Y-score (partner→DCAF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	EPPIN →	+0.006	+4.922	.005	.009	3	1
BLOOD_Leukemia	OR9K2 →	+0.012	+5.539	.007	.003	3	1
BLOOD_Leukemia	ARSH →	+0.012	+4.922	<.001	.009	3	1
LARGE_INTESTINE	MS4A18 →	+0.028	+4.095	<.001	.009	3	1
LARGE_INTESTINE	F11 →	+0.073	+4.467	<.001	.004	3	1
CNS	HTR3B →	+0.368	+4.981	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

EPPIN by DCAF4 expression — BLOOD_Leukemia

Explore this box plot interactively →