Across TCGA cell cohorts, DCAF12L2 mutation is significantly associated with the RNA expression of many other genes, with 191 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DCAF12L2-associated genes across cancer lineages are MYO5C, GRSF1, and RNF125. Each is linked with DCAF12L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCAF12L2-to-partner and partner-to-DCAF12L2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF12L2→partner) and Y-score (partner→DCAF12L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MYO5C →	+0.923	+3.212	.007	.006	3	2
LARGE_INTESTINE	GRSF1 →	+0.608	+3.212	<.001	.006	3	2
LARGE_INTESTINE	RNF125 →	+1.069	+3.064	<.001	.009	3	1
LARGE_INTESTINE	PRX →	+0.669	+3.212	<.001	.006	3	1
LARGE_INTESTINE	BCAS2 →	+0.557	+3.064	.003	.009	3	1
LARGE_INTESTINE	SYF2 →	+0.506	+3.212	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 191 associations by consensus.

Exploration

DCAF12L2 survival (RNA) · tumor vs normal (RNA) · all DCAF12L2 data types