Across TCGA patient cohorts, DCAF12L1 mutation is significantly associated with the total protein of many other genes, with 69 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCAF12L1-associated genes across cancer lineages are Caspase-7-cleavedD198, Cyclin-B1, and 14-3-3_beta. Each is linked with DCAF12L1 in more than 4 cancer types. Because this analysis shows association rather than direction, both DCAF12L1-to-partner and partner-to-DCAF12L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF12L1→partner) and Y-score (partner→DCAF12L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.932	+2.736	<.001	<.001	3	5
UCEC	Cyclin-B1 →	+0.563	+2.906	.001	.001	3	4
LUSC	14-3-3_beta →	-0.142	-2.691	.002	.006	3	3
LUSC	NF2 →	+0.276	+2.009	.001	.018	3	3
LUSC	STAT5a →	+0.430	+3.321	.047	.009	3	3
STAD	FASN →	+0.452	+3.337	.005	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

Exploration

DCAF12L1 survival (RNA) · tumor vs normal (RNA) · all DCAF12L1 data types