Across TCGA cell cohorts, DCAF12L1 mutation is significantly associated with the RNA expression of many other genes, with 281 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DCAF12L1-associated genes across cancer lineages are DNAAF6, FAM3D, and OR1L6. Each is linked with DCAF12L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCAF12L1-to-partner and partner-to-DCAF12L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF12L1→partner) and Y-score (partner→DCAF12L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	DNAAF6 →	+0.022	+3.345	<.001	.007	3	2
BLOOD_Lymphoma	FAM3D →	+0.114	+2.754	<.001	.009	3	2
LUNG_SCLC	OR1L6 →	+0.038	+4.614	<.001	<.001	3	2
BLOOD_Leukemia	H2BW2 →	+0.104	+4.234	<.001	.003	3	2
CNS	TEX55 →	+0.049	+5.321	<.001	.005	3	1
CNS	OR11H6 →	+0.021	+5.321	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 281 associations by consensus.

Exploration

DCAF12L1 survival (RNA) · tumor vs normal (RNA) · all DCAF12L1 data types