DCAF11

Across TCGA patient cohorts, DCAF11 mutation is significantly associated with the RNA expression of many other genes, with 1,231 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCAF11-associated genes across cancer lineages are FAM242E, PLTP, and TNNC2. Each is linked with DCAF11 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCAF11-to-partner and partner-to-DCAF11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM242E grouped by DCAF11-low versus DCAF11-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF11→partner) and Y-score (partner→DCAF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	FAM242E →	+0.062	+3.634	<.001	<.001	3	2
UCEC	PLTP →	-0.785	-2.662	.005	<.001	3	2
UCEC	TNNC2 →	-0.770	-2.321	.006	.006	3	2
UCEC	PARD6A →	+0.960	+3.321	<.001	<.001	3	2
UCEC	VAC14 →	+0.402	+2.695	<.001	<.001	3	2
UCEC	TANGO6 →	+0.394	+3.364	.008	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,231 associations by consensus.

FAM242E by DCAF11 expression — STAD

Explore this box plot interactively →