DCAF11

Across TCGA patient cohorts, DCAF11 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCAF11-associated genes across cancer lineages are Caspase-7-cleavedD198, G6PD, and PRAS40_pT246. Each is linked with DCAF11 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCAF11-to-partner and partner-to-DCAF11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by DCAF11-low versus DCAF11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF11→partner) and Y-score (partner→DCAF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.871	+2.019	<.001	.017	3	2
SKCM	G6PD →	-0.195	-3.000	.044	.035	3	1
SKCM	PRAS40_pT246 →	+0.149	+3.012	.041	.018	3	1
SKCM	Src →	-0.322	-3.169	.002	.018	3	1
SKCM	Chk2 →	-0.259	-2.321	.012	.033	3	1
SKCM	c-Jun_pS73 →	+0.168	+1.891	.008	.030	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Caspase-7-cleavedD198 by DCAF11 expression — UCEC

Explore this box plot interactively →