DCAF11

Across TCGA cell cohorts, DCAF11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,231 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible DCAF11-associated GO terms across cancer lineages are Cellular response to starvation, Establishment of vesicle localization, and Negative regulation of mRNA splicing, via spliceosome. Each is linked with DCAF11 in more than 12 cancer types. Because this analysis shows association rather than direction, both DCAF11-to-partner and partner-to-DCAF11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to starvation grouped by DCAF11-low versus DCAF11-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF11→partner) and Y-score (partner→DCAF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Cellular response to starvation →	+0.053	+0.718	<.001	<.001	3	13
KIDNEY	Establishment of vesicle localization →	+0.047	+0.762	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mRNA splicing, via spliceosome →	+0.106	+0.890	.004	.004	2	13
STOMACH	Positive regulation of TOR signaling →	+0.086	+0.817	.004	.002	3	11
PANCREAS	Regulation of protein localization to nucleus →	+0.070	+0.775	<.001	<.001	3	11
LUNG_SCLC	Positive regulation of stem cell population maintenance →	+0.128	+0.718	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,231 associations by consensus.

Cellular response to starvation by DCAF11 expression — LUNG_SCLC

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