DCAF10

Across TCGA pan-cancer cohorts, DCAF10 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated DCAF10 data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher DCAF10 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DCAF10 expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

PDAC, HNSC, and CCRCC are the cancer types where DCAF10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	III,IV	0.974	0.219	.001	17	view →
HNSC	DFS	Median	All	0.971	0.919	.026	9	view →
CCRCC	OS	Median	II,III,IV	0.416	1.000	.012	6	view →
UCEC	DFS	Median	II,III,IV	0.521	0.880	.037	4	view →
LUAD	OS	Quartile	All	0.933	1.000	.030	1	view →
LSCC	DFS	Tertile	All	0.834	0.702	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

DCAF10–PDAC (DFS)

Open the PDAC breakdown →