DBX2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DBX2 mutation is significantly associated with the RNA expression of many other genes, with 1,150 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DBX2-associated genes across cancer lineages are RPL36AP55, RN7SL248P, and PICART1. Each is linked with DBX2 in more than 2 cancer types. Because this analysis shows association rather than direction, both DBX2-to-partner and partner-to-DBX2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DBX2→partner) and Y-score (partner→DBX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
READRPL36AP55 →+0.262+5.219<.001.00633
UCECRN7SL248P →+0.072+3.500<.001.00232
SKCMPICART1 →+0.499+2.845<.001.00132
UCECATP5PD →+0.407+3.459.007.00532
CESCMIR4294 →+0.735+5.010<.001.00932
READRPS7P9 →+0.203+5.039<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,150 associations by consensus.

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