DBX1

Across TCGA cell cohorts, DBX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 471 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible DBX1-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, non-stop decay, Positive regulation of stem cell population maintenance, and Response to endoplasmic reticulum stress. Each is linked with DBX1 in more than 3 cancer types. Because this analysis shows association rather than direction, both DBX1-to-partner and partner-to-DBX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear-transcribed mRNA catabolic process, non-stop decay grouped by DBX1-low versus DBX1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DBX1→partner) and Y-score (partner→DBX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Nuclear-transcribed mRNA catabolic process, non-stop decay →	+0.077	+0.007	.002	.008	3	4
SOFT_TISSUE	Positive regulation of stem cell population maintenance →	+0.047	+0.844	<.001	.009	3	3
BREAST	Response to endoplasmic reticulum stress →	+0.071	+0.010	<.001	.007	3	3
LUNG_NSCLC_LUAD	Export across plasma membrane →	-0.062	-0.013	.003	.001	3	3
LUNG_NSCLC_LUAD	Mitotic cytokinesis →	+0.045	+0.014	.001	<.001	3	3
LUNG_SCLC	Regulation of T-helper 1 cell cytokine production →	-0.624	-0.941	.005	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 471 associations by consensus.

Nuclear-transcribed mRNA catabolic process, non-stop decay by DBX1 expression — BREAST

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