DBX1

Across TCGA cell cohorts, DBX1 mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DBX1-associated genes across cancer lineages are SLC32A1, C6orf118, and TTLL2. Each is linked with DBX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DBX1-to-partner and partner-to-DBX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC32A1 grouped by DBX1-low versus DBX1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DBX1→partner) and Y-score (partner→DBX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SLC32A1 →	+0.585	+4.223	<.001	.001	3	1
BLOOD_Leukemia	C6orf118 →	+0.049	+3.450	<.001	.004	3	1
BLOOD_Leukemia	TTLL2 →	+0.341	+3.736	<.001	.005	3	1
BLOOD_Leukemia	KLRD1 →	+0.138	+4.091	.001	.002	3	1
BLOOD_Leukemia	IL36A →	+1.028	+3.656	<.001	.006	3	1
BLOOD_Leukemia	RHCG →	+0.072	+3.729	.007	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

SLC32A1 by DBX1 expression — BLOOD_Leukemia

Explore this box plot interactively →