DBR1

Across TCGA patient cohorts, DBR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,002 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DBR1-associated proteins across cancer lineages are FXR1, SMC2, and SMC4. Each is linked with DBR1 in more than 6 cancer types. Because this analysis shows association rather than direction, both DBR1-to-partner and partner-to-DBR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DBR1 versus FXR1 in HNSC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DBR1→partner) and Y-score (partner→DBR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FXR1 →	+0.430	+0.717	<.001	<.001	3	7
GBM	SMC2 →	+0.511	+0.197	.001	.002	3	6
GBM	SMC4 →	+0.595	+0.241	.003	.002	3	6
OV	GMPS →	+0.647	+0.486	<.001	<.001	3	6
LSCC	HMCES →	+0.645	+0.713	<.001	<.001	3	6
UCEC	MCM2 →	+0.627	+0.493	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,002 associations by consensus.

DBR1 vs FXR1 — HNSC

Explore this scatter interactively →