DBR1

Across TCGA patient cohorts, DBR1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,116 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DBR1-associated genes across cancer lineages are TFDP2, MRPL3, and TOPBP1. Each is linked with DBR1 in more than 7 cancer types. Because this analysis shows association rather than direction, both DBR1-to-partner and partner-to-DBR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DBR1 versus TFDP2 in LSCC, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DBR1→partner) and Y-score (partner→DBR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TFDP2 →	+0.931	+0.393	<.001	<.001	3	8
HNSC	MRPL3 →	+0.756	+0.270	<.001	<.001	3	8
LSCC	TOPBP1 →	+0.987	+0.430	<.001	<.001	3	8
LSCC	ARMC8 →	+0.649	+0.402	<.001	<.001	3	7
HNSC	EIF2A →	+0.688	+0.224	<.001	<.001	3	7
LSCC	CCDC58 →	+0.833	+0.395	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,116 associations by consensus.

DBR1 vs TFDP2 — LSCC

Explore this scatter interactively →